Dr. Jinghui Zang
St. Jude Endowed Chair in Bioinformatics, St. Jude Children’s Research Hospital, Memphis, Tennessee
UConn ’94

Co-sponsored by Dept. Molecular and Cell Biology, The Institute for Systems Genomics, and the School of Computing

Genomic Variants in Pediatric Cancer: Driver Discovery, Clinical Testing and Computational Analysis

Jinghui Zhang’s research focuses on developing and applying genomic-based approaches for improving the treatment and outcome of pediatric cancer. Her research on innovative computational methods development has greatly advanced discovery, interpretation, and visualization of somatic and germline variants. She has built a new Computational Biology Department at St Jude by recruiting and mentoring multi-disciplinary computational experts to establish innovative research programs focusing on pediatric cancer. An advocate for genomic data sharing, Zhang initiated the development of St. Jude Cloud, the world’s largest pediatric cancer data sharing platform. She received a PhD in Genetics from the University of Connecticut in 1994 for research done with the late Claire M. Berg (MCB). She continued work at the NCBI for many years, worked in industry (Glaxo Wellcome, Celera Genomics) and at the National Cancer Institute. Since 2010 she has been at the St. Jude Children’s Research Hospital in Memphis. She is an elected fellow of the International Society for Computational Biology. 

Helena Heyer-Gray, Klassen Lab

Abaecin-2 modulates interactions in a fungus-growing ant symbiosis by changing copper availability

Join us in the Logic Colloquium for a talk by

Jonas Raab (Trinity College Dublin)

“Modal QUARC and Barcan”

I develop a modal extension of the Quantified Argument Calculus (QUARC)—a novel logical system introduced by Hanoch Ben-Yami. QUARC is meant to better capture the logic of natural language. The purpose of this paper is to develop a variable domain semantics for modal QUARC (M-QUARC), and to show that even if the usual restrictions are imposed on models with variable domains, M-QUARC-analogues of the Barcan and Converse Barcan formulas still are not validated. I introduce new restrictions—restrictions on the extension of the predicates—and show that with these in place, the Barcan and Converse Barcan formulas are valid. The upshot is that M-QUARC sheds light on the in-/validity of such formulas.

https://logic.uconn.edu/calendar/